Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Kathy Y. Liu; Rogier A. Kievit; Kamen A. Tsvetanov; Matthew J. Betts; Emrah Düzel; James B. Rowe; Cam-CAN; Robert Howard; Dorothea Hämmerer

doi:10.1038/s41467-020-15410-w

Nature Communications (Apr 2020)

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Kathy Y. Liu,
Rogier A. Kievit,
Kamen A. Tsvetanov,
Matthew J. Betts,
Emrah Düzel,
James B. Rowe,
Cam-CAN,
Robert Howard,
Dorothea Hämmerer

Affiliations

Kathy Y. Liu: Division of Psychiatry, University College London
Rogier A. Kievit: Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge
Kamen A. Tsvetanov: Cambridge Centre for Ageing and Neuroscience (Cam-CAN), University of Cambridge and MRC Cognition and Brain Sciences Unit
Matthew J. Betts: German Center for Neurodegenerative Diseases (DZNE)
Emrah Düzel: German Center for Neurodegenerative Diseases (DZNE)
James B. Rowe: Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge
Cam-CAN
Robert Howard: Division of Psychiatry, University College London
Dorothea Hämmerer: German Center for Neurodegenerative Diseases (DZNE)

DOI: https://doi.org/10.1038/s41467-020-15410-w
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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