Immune-mediated conditions and cellular biomarkers for early diagnosis of oral diseases
Guangzhao Guan,
Ajith Polonowita,
Qing Sun,
Li Mei
Affiliations
Guangzhao Guan
Department of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, 310 Great King Street, Dunedin 9016, New Zealand; Corresponding authors.
Ajith Polonowita
Department of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, 310 Great King Street, Dunedin 9016, New Zealand
Qing Sun
Department of Oral Diagnostic and Surgical Sciences, Faculty of Dentistry, University of Otago, 310 Great King Street, Dunedin 9016, New Zealand
Li Mei
Department of Oral Sciences, Faculty of Dentistry, University of Otago, 310 Great King Street, Dunedin 9016, New Zealand; Corresponding authors.
Oral signs and symptoms are frequently the first manifestation of immunological conditions. The dentists can therefore play an important role in the detection and during the management phase of the multidisciplinary treatment. Precise and early diagnosis increases the efficiency and efficacy of treatment strategy. This review provided an update of the immune system, the common immunological conditions that show oral clinical signs and symptoms, and guidance as to the appropriate investigation needed to differentiate and correctly diagnoses these conditions.