Autologous fat transfer for hand rejuvenation: A systematic review on technique and outcome
Nicolas Vermeersch,
Maxime De Fré,
Veronique Verhoeven,
Judith E. Hunter,
Thierry Tondu,
Filip E.F. Thiessen
Affiliations
Nicolas Vermeersch
Department of Plastic, Reconstructive, and Aesthetic Surgery, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, B-2650 Antwerp, Belgium; Department of Plastic, Reconstructive, and Aesthetic Surgery, Ziekenhuis Netwerk Antwerpen, Lindendreef 1, B-2020, Antwerp, Belgium; Corresponding author: Dr. Nicolas Vermeersch.
Maxime De Fré
Department of Plastic, Reconstructive, and Aesthetic Surgery, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, B-2650 Antwerp, Belgium; Department of Plastic, Reconstructive, and Aesthetic Surgery, Ziekenhuis Netwerk Antwerpen, Lindendreef 1, B-2020, Antwerp, Belgium
Veronique Verhoeven
Department of Primary and Interdisciplinary Care (ELIZA), University of Antwerp, Antwerp, Belgium
Judith E. Hunter
Department of Plastic and Reconstructive Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
Thierry Tondu
Department of Plastic, Reconstructive, and Aesthetic Surgery, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, B-2650 Antwerp, Belgium; Department of Plastic, Reconstructive, and Aesthetic Surgery, Ziekenhuis Netwerk Antwerpen, Lindendreef 1, B-2020, Antwerp, Belgium
Filip E.F. Thiessen
Department of Plastic, Reconstructive, and Aesthetic Surgery, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, B-2650 Antwerp, Belgium; Department of Plastic, Reconstructive, and Aesthetic Surgery, Ziekenhuis Netwerk Antwerpen, Lindendreef 1, B-2020, Antwerp, Belgium
Background: Age-related changes to the dorsum of the hand present as dyschromia, soft-tissue atrophy, and volume loss, resulting in wrinkles and prominent deep structures. Volume augmentation by means of autologous fat transfer (AFT) is one of the options to rejuvenate the hand; theoretically, autologous fat is the ideal filler because of durability and biocompatibility. Objective: This systematic review aims to summarize and describe the current evidence on the technique, effectiveness, and safety of AFT in hand rejuvenation. Methods: Three major databases, PubMed, Embase, and Web of Science, were systematically searched up to November 2020 for studies reporting on AFT and hand rejuvenation. Results: A total of 10 articles were included, reporting on a total of 320 patients treated by AFT to improve the aesthetic appearance of the dorsum of the hand. Some degree of postoperative oedema was present in nearly all patients. Other complications were infection (0.67%), cysts/irregularities (1.3%), temporary dysesthesia (5.3%), and ecchymosis (7%). There were no major complications. Of all patients, 97.6% self-reported to be satisfied with the result. Conclusions: Overall, by combining the current evidence, AFT is considered a promising and safe technique to rejuvenate the aging hand with very high patient satisfaction. Future research, using validated patient questionnaires, objective volumetric measurements, and longer follow-up, is needed to confirm these results. Level of Evidence: 3
