Nature Communications (Mar 2021)

Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection

  • Zhongfang Wang,
  • Xiaoyun Yang,
  • Jiaying Zhong,
  • Yumin Zhou,
  • Zhiqiang Tang,
  • Haibo Zhou,
  • Jun He,
  • Xinyue Mei,
  • Yonghong Tang,
  • Bijia Lin,
  • Zhenjun Chen,
  • James McCluskey,
  • Ji Yang,
  • Alexandra J. Corbett,
  • Pixin Ran

DOI
https://doi.org/10.1038/s41467-021-22036-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 8

Abstract

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T cells compose a critical component of the immune response to coronavirus infection with SARS-CoV-2. Here the authors characterise the T cell response to SARS CoV-2 in patients and their close contacts, and show the presence of SARS-CoV-2 specific T cells in the absence of detectable virus infection.