Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

Abstract

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.

Keywords

• Plasmodium falciparum
• atovaquone-proguanil
• therapeutic failure
• dispatch
• France
• Democratic Republic of Congo