Indian Dermatology Online Journal (Jan 2023)

Chronic oro-genital ulcerations as a presenting feature of chronic eosinophilic leukemia: A case report

  • Jigna Padhiyar,
  • Nayan Patel,
  • Megha Lakum,
  • Himal Shah

DOI
https://doi.org/10.4103/idoj.idoj_477_22
Journal volume & issue
Vol. 14, no. 4
pp. 524 – 526

Abstract

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Hypereosinophilia can be primary, including idiopathic hypereosinophilic syndrome (HES) and chronic eosinophilic leukemia, or secondary/reactive to various infective and non-infective stimuli. Chronic oro-genital ulcerations can occur due to various dermatological and non-dermatological disorders, and many times it serves as a useful indicator of an underlying systemic disorder. Hence, a case presenting with chronic oro-genital ulcerations needs a thorough evaluation. We are reporting an interesting case of a middle-aged male who had chronic oro-genital ulcerations as a presenting feature of chronic eosinophilic leukemia with FIP1L1-PDGFRA fusion (FIP1-like 1/platelet-derived growth factor receptor alpha). The patient's oro-genital ulcerations responded excellently to imatinib.

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