Frontiers in Human Neuroscience (Apr 2015)
Age-related striatal BOLD changes without changes in behavioral loss aversion
- Hans C Breiter,
- Hans C Breiter,
- Hans C Breiter,
- Hans C Breiter,
- Vijay eViswanathan,
- Vijay eViswanathan,
- Sang eLee,
- Sang eLee,
- Sang eLee,
- Jodi M Gilman,
- Byoung Woo Kim,
- Byoung Woo Kim,
- Byoung Woo Kim,
- Byoung Woo Kim,
- Nick eLee,
- Nick eLee,
- Laura eChamberlain,
- Laura eChamberlain,
- Kalyan eRaman,
- Kalyan eRaman,
- Kalyan eRaman,
- Myung Joo Lee,
- Myung Joo Lee,
- Myung Joo Lee,
- Myung Joo Lee,
- Jake eKuster,
- Jake eKuster,
- Sherri Lynn Livengood,
- Sherri Lynn Livengood,
- Daniel Benjamin Stern,
- Daniel Benjamin Stern,
- Bobby eCalder,
- Bobby eCalder,
- Frank J Mulhern,
- Frank J Mulhern,
- Anne eBlood,
- Anne eBlood,
- Anne eBlood
Affiliations
- Hans C Breiter
- Northwestern University Feinberg School of Medicine
- Hans C Breiter
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Hans C Breiter
- Massachusetts General Hospital
- Hans C Breiter
- Northwestern University and Massachusetts General Hospital
- Vijay eViswanathan
- Northwestern University
- Vijay eViswanathan
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Sang eLee
- Massachusetts General Hospital
- Sang eLee
- Northwestern University Feinberg School of Medicine
- Sang eLee
- Northwestern University and Massachusetts General Hospital
- Jodi M Gilman
- Massachusetts General Hospital
- Byoung Woo Kim
- Massachusetts General Hospital
- Byoung Woo Kim
- Northwestern University Feinberg School of Medicine
- Byoung Woo Kim
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Byoung Woo Kim
- Northwestern University and Massachusetts General Hospital
- Nick eLee
- Loughborough University
- Nick eLee
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Laura eChamberlain
- Loughborough University
- Laura eChamberlain
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Kalyan eRaman
- Northwestern University
- Kalyan eRaman
- Northwestern University
- Kalyan eRaman
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Myung Joo Lee
- Massachusetts General Hospital
- Myung Joo Lee
- Northwestern University Feinberg School of Medicine
- Myung Joo Lee
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Myung Joo Lee
- Northwestern University and Massachusetts General Hospital
- Jake eKuster
- Massachusetts General Hospital
- Jake eKuster
- Northwestern University and Massachusetts General Hospital
- Sherri Lynn Livengood
- Northwestern University Feinberg School of Medicine
- Sherri Lynn Livengood
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Daniel Benjamin Stern
- Northwestern University Feinberg School of Medicine
- Daniel Benjamin Stern
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Bobby eCalder
- Northwestern University
- Bobby eCalder
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Frank J Mulhern
- Northwestern University
- Frank J Mulhern
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- Anne eBlood
- Massachusetts General Hospital
- Anne eBlood
- Northwestern University and Massachusetts General Hospital
- Anne eBlood
- Northwestern University, Wayne State University, University of Michigan, Loughborough University School of Business and Economics (UK) and Massachusetts General Hospital/Harvard University
- DOI
- https://doi.org/10.3389/fnhum.2015.00176
- Journal volume & issue
-
Vol. 9
Abstract
Loss aversion (LA), the idea that negative valuations have a higher psychological impact than positive ones, is considered an important variable in consumer research. The literature on aging and behavior suggests older individuals may show more LA, although it is not clear if this is an effect of aging in general (as in the continuum from age 20 and 50 years), or of the state of older age (e.g., past age 65 years). We also have not yet identified the potential biological effects of aging on the neural processing of LA. In the current study we used a cohort of subjects with a 30 year range of ages, and performed whole brain functional MRI (fMRI) to examine the ventral striatum/nucleus accumbens (VS/NAc) response during a passive viewing of affective faces with model-based fMRI analysis incorporating behavioral data from a validated approach/avoidance task with the same stimuli. Our a priori focus on the VS/NAc was based on (1) the VS/NAc being a central region for reward/aversion processing, (2) its activation to both positive and negative stimuli, (3) its reported involvement with tracking LA. LA from approach/avoidance to affective faces showed excellent fidelity to published measures of LA. Imaging results were then compared to the behavioral measure of LA using the same affective faces. Although there was no relationship between age and LA, we observed increasing neural differential sensitivity (NDS) of the VS/NAc to avoidance responses (negative valuations) relative to approach responses (positive valuations) with increasing age. These findings suggest that a central region for reward/aversion processing changes with age, and may require more activation to produce the same LA behavior as in younger individuals, consistent with the idea of neural efficiency observed with high IQ individuals showing less brain activation to complete the same task.
Keywords
