Nature Communications (Jul 2022)
Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCR
- Kenneth Danh,
- Donna Grace Karp,
- Malvika Singhal,
- Akshaya Tankasala,
- David Gebhart,
- Felipe de Jesus Cortez,
- Devangkumar Tandel,
- Peter V. Robinson,
- David Seftel,
- Mars Stone,
- Graham Simmons,
- Anil Bagri,
- Martin A. Schreiber,
- Andreas Buser,
- Andreas Holbro,
- Manuel Battegay,
- Mary Kate Morris,
- Carl Hanson,
- John R. Mills,
- Dane Granger,
- Elitza S. Theel,
- James R. Stubbs,
- Laurence M. Corash,
- Cheng-ting Tsai
Affiliations
- Kenneth Danh
- Enable Biosciences Inc
- Donna Grace Karp
- Enable Biosciences Inc
- Malvika Singhal
- Enable Biosciences Inc
- Akshaya Tankasala
- Enable Biosciences Inc
- David Gebhart
- Enable Biosciences Inc
- Felipe de Jesus Cortez
- Enable Biosciences Inc
- Devangkumar Tandel
- Enable Biosciences Inc
- Peter V. Robinson
- Enable Biosciences Inc
- David Seftel
- Enable Biosciences Inc
- Mars Stone
- Vitalant Research Institute
- Graham Simmons
- Vitalant Research Institute
- Anil Bagri
- Cerus Corporation
- Martin A. Schreiber
- Department of Surgery, Oregon Health & Science University
- Andreas Buser
- Regional Blood Transfusion Service, Swiss Red Cross, University Hospital Basel, University of Basel
- Andreas Holbro
- Regional Blood Transfusion Service, Swiss Red Cross, University Hospital Basel, University of Basel
- Manuel Battegay
- Division of Infectious Diseases & Hospital Epidemiology, University Hospital Basel, University of Basel
- Mary Kate Morris
- California Department of Public Health
- Carl Hanson
- California Department of Public Health
- John R. Mills
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Dane Granger
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Elitza S. Theel
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- James R. Stubbs
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Laurence M. Corash
- Cerus Corporation
- Cheng-ting Tsai
- Enable Biosciences Inc
- DOI
- https://doi.org/10.1038/s41467-022-31796-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 8
Abstract
Neutralizing antibodies are critical for conferring immunity against SARS-CoV-2. Here, Dahn et al. report a PCR assay termed SONIA (Split-Oligonucleotide Neighboring Inhibition Assay) for measuring neutralizing antibodies against multiple SARS-CoV-2 strains in fingerprick dried blood spot samples.
