Utility of Immunofluorescence in the Diagnosis of Glomerulopathies

Abstract

Abstract Introduction: Glomerulopathies constitute aheterogeneous group of diseases that are difficult to diagnose and immunofluorescence is currently considered an invaluable technique to establish an adequate diagnosis and a correct therapeutic approach. Objective: To contribute to the updating of the scientific community in relation to the diagnosis of this pathology with the use of immunofluorescence. Methodology: A non-systematic bibliographic review was carried out in the databases available on the Internet such as: Scielo, Elsevier, Cochrane Library, PubMed, Intramed. This search was conducted in both Spanish and English. Results: 55 bibliographic sources were found, of which 30 relevant scientific articles were used and 25 were excluded because they did not meet the selection criteria. Discussion: Glomerulopathies comprise a group of diseases that affect renal function, they can be primary or secondary and have an acute or chronic and progressive course, with high morbidity and mortality worldwide, since they can lead patients to renal failure, Therefore, the use of diagnostic means such as immunofluorescence is an invaluable tool to achieve a specific diagnosis, which will result in an appropriate therapeutic approach for each patient. Conclusion: Immunofluorescence is an invaluable technique in the diagnosis of glomerulopathies that facilitates an adequate therapeutic approach for patients. And it allows to establish the specific type between the different variants of this group of diseases.

Keywords

• glomerulopathies, immunofluorescence, renal failure, glomerular filtration, immune complex deposits.