Imipenem and Meropenem: Comparison of In Vitro Activity, Pharmacokinetics, Clinical Trials and Adverse Effects

Affiliations

George G Zhanel: Departments of Medicine and Microbiology, Health Sciences Centre and Faculties of Pharmacy and Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Andrew E Simor: Department of Microbiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Lavern Vercaigne: Department of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
Lionell Mandell: Department of Infectious Diseases, McMaster University, Hamilton, Ontario, Canada
the Canadian Carbapenem Discussion Group

Abstract

OBJECTIVE: To compare and contrast imipenem and meropenem in terms of in vitro activity, pharmacokinetics, clinical efficacy and adverse effects.

ISSN: 1180-2332 (Print)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://onlinelibrary.wiley.com/journal/9575