Hyaline and Cystic Degeneration of Uterine Leiomyomas: CT and MR Imaging with Histopathological Sample Analyses
Camilo G. Sotomayor,
Carla Parra,
Maximiliano Miranda,
Juan Salvador Casas,
Gonzalo Cárdenas,
Álvaro Sanhueza,
Francisca Araya,
Iván Gallegos,
Sebastián Yévenes
Affiliations
Camilo G. Sotomayor
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Carla Parra
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Maximiliano Miranda
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Juan Salvador Casas
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Gonzalo Cárdenas
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Álvaro Sanhueza
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Francisca Araya
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Iván Gallegos
Pathology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Sebastián Yévenes
Abdominal and Pelvis Unit, Radiology Department, Clinical Hospital University of Chile, Faculty of Medicine, University of Chile, Independencia, Santiago 8380453, Chile
Leiomyomas are the most common solid benign uterine neoplasms; they are usually asymptomatic and are identified incidentally. Yet, responsive to stimulation by estrogens, leiomyomas may expand, potentially outgrowing their blood supply to undergo hemorrhage, fibrosis, calcification, and atrophy. These pathologic mechanisms commonly lead to leiomyomas degeneration, i.e., red, hyaline, cystic, or myxoid. Magnetic resonance (MR) imaging is the most accurate imaging technique for the characterization of leiomyomas. In cases of degeneration, variable features on T2-weighted and contrast-enhanced images can be found. With no recent radiologic pathologic correlation literature available on this matter, herewith, we provide computed tomography (CT)/MR imaging along with histopathological specimens of two young women who were diagnosed with hyaline or hyaline and cyst degeneration of uterine leiomyomas at our university hospital. We report on the imaging features of uterine leiomyomas using CT and MR imaging and discuss the available literature on imaging signs that may be suggestive of hyaline or cyst degeneration using either of the imaging examination methods.