Rare Tumors (Mar 2011)

Lung carcinoma with hypertrophic osteoarthropathy in a teenager

  • Jeremy Whelan,
  • Rowland O. Illing,
  • Rowan E. Miller

DOI
https://doi.org/10.4081/rt.2011.e8
Journal volume & issue
Vol. 3, no. 1
pp. e8 – e8

Abstract

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Hypertrophic osteoarthropathy (HOA) characterised by arthralgia, clubbing and periosteal proliferation of long bones, is rarely encountered in children and adolescents. Whereas in adults over 80% of cases are associated with malignancy, in children the majority of cases are due to non-neoplastic causes such as cystic fibrosis, bilary atresia and congenital heart disease. Up to 5% of adults with lung cancer demonstrate signs of HOA. However, lung cancer is extremely uncommon in children and young people. Here we report a case of lung adenocarcinoma in an 18 year old male associated with HOA present both at diagnosis and at subsequent disease progression.

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