Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
João Paulo Caldas,
André Silva-Pinto,
Ana Sofia Faustino,
Paulo Figueiredo,
António Sarmento,
Lurdes Santos
Affiliations
João Paulo Caldas
Correspondence to: Infectious Diseases Department, Centro Hospitalar Universitário de São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.; Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
André Silva-Pinto
Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
Ana Sofia Faustino
Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
Paulo Figueiredo
Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
António Sarmento
Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
Lurdes Santos
Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, Portugal
Septic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires’ disease is mainly due to Legionella pneumophila serogroup 1 but it can be caused by other serogroups and species not detected by the urinary antigen test. Anti-tumour necrosis factor α therapy may increase the risk of invasive fungal infection, which carry a poor prognosis. We present a challenging case of a septic shock due to Legionella pneumophila and Saprochaete clavata infections, with a review of the two infections presented.