Assessing Sensitivity and Specificity of Surveillance Case Definitions for Zika Virus Disease

Abstract

We evaluated performance of 5 case definitions for Zika virus disease surveillance in a human cohort during an outbreak in Singapore, August 26–September 5, 2016. Because laboratory tests are largely inaccessible, use of case definitions that include rash as a required clinical feature are useful in identifying this disease.

Keywords

• Zika virus disease
• Zika virus
• viruses
• case definition
• sensitivity
• specificity