Control methods for non-smoking nicotine-containing products

Abstract

Non-smoking products for oral consumption are a growing segment of the nicotinecontaining products market and, therefore, the study of the component composition and toxicological load during its consumption is an urgent task. The toxic components of nicotine-containing products are the subject of research in scientific laboratories and are carried out by various methods. Studies have been monitored for potential toxicity determinations of tobacco and non-tobacco smokeless products. The article presents the results of monitoring methods for determining toxic components that determine the risk of nonsmoking products, carried out at the Federal State Budgetary Scientific Institution ARSRCTTP. As a result of the research, methods for the quantitative determination of nicotine content have been determined and the method for the determination of tobacco-specific nitrosamines (TSNA) using high-performance liquid chromatography in the product under study has been validated.

Keywords

• nicotine-containing products
• raw tobacco
• non-smoking product
• toxicity
• nicotine
• tobacco specific nitrosamines
• nitrosonornicotine (nnn)
• 4-(n-methyl-n-nitrosamino-)–1- (3-pyridyl-) – 1-butanone (nnk)
• ph
• water activity