Advanced Herbal Medicine (Sep 2017)
The effect of Cornus mas in preventing recurrent urinary tract infections in women
Abstract
Background:Urinary tract infections(UTIs)are one of the most common and the second leading infections,after respiratory tract infections,in women.Currently,various chemical drugs are used to prevent the UTIs.Chemical drugs may cause antibiotic resistance and resistant strains are likely to grow in the long-term treatment with antibiotics.The aim of this study is to investigate the effect of Cornusmas in preventing recurrent UTIs in women aged15-45 years referring to AyatollahKashani Hospital ClinicShahrekord Methods:This experimental study was conducted on42women aged15-45 years referring to Ayatollah Kashani Hospital Clinic of Shahrekord and diagnosed with chronic cystitis.The exclusion criteria were neurogenic bladder,genitourinary system anatomical abnormalities (hydronephrosis,ureterocele stone,etc),and bacterial resistance.The women were randomly assigned to2groups.At baseline, the women were examined for any functional and anatomical disorders and, if necessary, underwent ultrasound.After the current UTIs were treated and the women clinically recovered,one group was administered with Cornusmas tablet500mg and another group administered with placebo for6months.All the women were followedup for6 months.Every2 months,the patients were clinically examined and their urine cultures were investigated for the clinical signs of cystitis.As the symptoms of the UTIs occur,the patients were recommended to refer for repeated urine culture Resulte:In our study, nosignificant difference was observed between the groups in terms of recurrent UTI recurrence,although there were differences(P>0.005).Positive urine culture in Cornusmas group was19% and in placebo was33.4%. In terms of dysuria in6 months and the second time there was significant difference between placebo and Cornusmas(P=0.004)Dysuria in Cornusmas group was14.2% and in placebo was56.2% Conclusions:Cornusmas can decrease dysuria and frequent urination in patients with recurrent UTIs.key words:Cornusmas,UTI,women
