Diagnostics (Jun 2023)

Schwannoma: A Rare Case of Submucosal Gastric Tumor

  • Cosmina Fugărețu,
  • Cătalin Mișarca,
  • Lucian Petcu,
  • Raluca Șoană,
  • Andrada Cîrnațiu,
  • Marin Valeriu Surlin,
  • Stefan Patrascu,
  • Sandu Ramboiu

DOI
https://doi.org/10.3390/diagnostics13122073
Journal volume & issue
Vol. 13, no. 12
p. 2073

Abstract

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Schwannoma is a tumor that originates from the Schwann cells that surround a neuron’s axon. This tumor is very rare in the gastrointestinal tract and develops submucosally from intestinal nerve plexuses. The most common location for gastrointestinal schwannomas is the stomach, where they account for only 0.2% of gastric tumors. We present the case of a 56-year-old asymptomatic patient who was diagnosed, following a routine ultrasound examination, with an abdominal tumor. An abdominal MRI confirmed the gastric origin of the tumor. Although a subsequent upper-digestive endoscopic ultrasound was performed, a definitive diagnosis could not be established. Thus, a laparoscopic wedge resection of the stomach was performed. The immunohistochemical examination of the tumor established the diagnosis of benign schwannoma. Despite the availability of advanced endoscopy and imaging techniques, the diagnosis of gastric schwannoma is very rarely preoperative. The immunohistochemical identification of S-100 on the surgical specimen confirmed the diagnosis.

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