From Bench to Bedside in Rheumatoid Arthritis from the “2022 GISEA International Symposium”

Antonio Vitale; Stefano Alivernini; Roberto Caporali; Giulia Cassone; Dario Bruno; Luca Cantarini; Giuseppe Lopalco; Maurizio Rossini; Fabiola Atzeni; Ennio Giulio Favalli; Fabrizio Conti; Elisa Gremese; Florenzo Iannone; Gian Franco Ferraccioli; Giovanni Lapadula; Marco Sebastiani

doi:10.3390/jcm12020527

Journal of Clinical Medicine (Jan 2023)

From Bench to Bedside in Rheumatoid Arthritis from the “2022 GISEA International Symposium”

Antonio Vitale,
Stefano Alivernini,
Roberto Caporali,
Giulia Cassone,
Dario Bruno,
Luca Cantarini,
Giuseppe Lopalco,
Maurizio Rossini,
Fabiola Atzeni,
Ennio Giulio Favalli,
Fabrizio Conti,
Elisa Gremese,
Florenzo Iannone,
Gian Franco Ferraccioli,
Giovanni Lapadula,
Marco Sebastiani

Affiliations

Antonio Vitale: Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet’s Disease Clinic, University of Siena, 53100 Siena, SI, Italy
Stefano Alivernini: Immunology Research Core Facility, Gemelli Science and Technology Park, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, RM, Italy
Roberto Caporali: Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, 20122 Milano, MI, Italy
Giulia Cassone: Rheumatology Unit, Azienda Ospedaliera Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, MO, Italy
Dario Bruno: Immunology Research Core Facility, Gemelli Science and Technology Park, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, RM, Italy
Luca Cantarini: Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet’s Disease Clinic, University of Siena, 53100 Siena, SI, Italy
Giuseppe Lopalco: Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, 70121 Bari, BA, Italy
Maurizio Rossini: Rheumatology Unit, University of Verona, Policlinico G.B. Rossi, Piazzale A. Scuro, 37134 Verona, VR, Italy
Fabiola Atzeni: Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, 98122 Messina, ME, Italy
Ennio Giulio Favalli: Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, 20122 Milano, MI, Italy
Fabrizio Conti: Lupus Clinic, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University of Rome, 00185 Roma, RM, Italy
Elisa Gremese: Immunology Research Core Facility, Gemelli Science and Technology Park, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, RM, Italy
Florenzo Iannone: Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, 70121 Bari, BA, Italy
Gian Franco Ferraccioli: Scuola di Medicina, Università Cattolica del Sacro Cuore, 20123 Milano, MI, Italy
Giovanni Lapadula: Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, 70121 Bari, BA, Italy
Marco Sebastiani: Rheumatology Unit, Azienda Ospedaliera Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, MO, Italy

DOI: https://doi.org/10.3390/jcm12020527
Journal volume & issue: Vol. 12, no. 2
p. 527

Abstract

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While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors of drug response give hope for future tailored therapeutic strategies and a personalized medicine approach in inflammatory arthropathies. Here, we discuss the main pathogenetic mechanisms and therapeutic approaches towards precision medicine in rheumatoid arthritis from the 2022 International GISEA/OEG Symposium.

Published in Journal of Clinical Medicine

ISSN: 2077-0383 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/jcm

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