Communications Medicine (Dec 2021)

Implementation of a fully remote randomized clinical trial with cardiac monitoring

  • Jacob J. Mayfield,
  • Neal A. Chatterjee,
  • Peter A. Noseworthy,
  • Jeanne E. Poole,
  • Michael J. Ackerman,
  • Jenell Stewart,
  • Patricia J. Kissinger,
  • John Dwyer,
  • Sybil Hosek,
  • Temitope Oyedele,
  • Michael K. Paasche-Orlow,
  • Kristopher Paolino,
  • Paul A. Friedman,
  • Chloe Waters,
  • Jessica Moreno,
  • Hannah Leingang,
  • Kate B. Heller,
  • Susan A. Morrison,
  • Meighan L. Krows,
  • Ruanne V. Barnabas,
  • Jared Baeten,
  • Christine Johnston,
  • COVID-19 Early Treatment Team,
  • Arun R. Sridhar

DOI
https://doi.org/10.1038/s43856-021-00052-w
Journal volume & issue
Vol. 1, no. 1
pp. 1 – 10

Abstract

Read online

Mayfield et al. describe the implementation and feasibility of an exclusively remote randomized clinical trial of hydroxychloroquine and azithromycin for the treatment of COVID-19. The trial included monitoring of cardiovascular safety which was successfully done using digital technologies.