Emerging Infectious Diseases (Mar 2008)

Mutations in Influenza A Virus (H5N1) and Possible Limited Spread, Turkey, 2006

  • Ender Altiok,
  • Fulya Taylan,
  • Osman Ş. Yenen,
  • Gülşah Demirkeser,
  • Mürvet Bozaci,
  • Derya Önel,
  • Birsen Akcadag,
  • A. Selma Iyisan,
  • Meral Ciblak,
  • Emel Bozkaya,
  • Sirin Yuksel,
  • Selim Badur

DOI
https://doi.org/10.3201/eid1403.061237
Journal volume & issue
Vol. 14, no. 3
pp. 491 – 492

Abstract

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We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died.

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