Química Nova (Jan 1998)

Stereoselective sodium borohydride reductions of cyclopentanones: influence of ceric chloride on the stereochemistry of reaction

  • Constantino Mauricio Gomes,
  • Matias Luiz Gonzaga de Oliveira,
  • Silva Gil Valdo José da,
  • Barbieri Emerson,
  • Gambardella Maria Teresa do Prado

Journal volume & issue
Vol. 21, no. 6
pp. 719 – 721

Abstract

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In this paper we describe the reduction by NaBH4 of some cyclopentanones containing an oxygenated function at the side chain position beta to the carbonyl group, both in the presence and in the absence of CeCl3. Some suggestions for the rationalization of the results are discussed, considering the stereochemical course of the reactions.

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