Use of a glucomannan polymer to reduce the effects of mycotoxin-contaminated diets in finishing pigs

Abstract

The use of feed additives with mycotoxin adsorption capacity is a common strategy for controlling negative effects of mycotoxins in swine production systems. However, adsorbents that may results very effective under experimental conditions, i.e. when feed contamination level is rather high, do not necessarily retain their efficacy when tested under field conditions feed with generally low mycotoxin contamination. In this study, the effects of diets artificially contaminated with aflatoxin B1 or ochratoxin A on fattening performance and serum chemistry of fattening pigs are investigated. Moreover, the ability of a commercial glucomannan polymer (Gm polimer) to reduce or eliminate the effects of the contaminated feeds is tested. Thirty heavy pigs (BW = 110±10.6 kg) were fed 6 diets (n = 5 pigs/diet) for 4 weeks until slaughtering. Diets were: control without toxin added (C); added with 0.02 ppm of aflatoxin B1 (AFB1); added with 0.05 ppm of ochratoxin A (OTA); other three diets as the previous but the addition of 2.0 g/kg of Gm polymer (C-GM, AFB1-GM, OTA-GM). Daily weight gain (ADG) and Feed efficiency ratio (FE) were measured every two weeks. Data were analyzed with a two-way ANOVA that included the fixed effect of diet, time and their interaction. After the first 2 weeks the ADG did not differ significantly between the diets, even if the ADG of AFB1 diet was about 20% lower than AFB1-Gm or C. In the last 2 weeks the ADG of AFB1 diet was significantly lover than the other diets (P<0.01) and was about one-half of the values reported for the same group in the first period. The contamination with ochratoxin A did not affect fattening performance of pigs during the whole experimental period. No damages were found in kidneys of all diets. Moreover, no evidence of association between observed liver damages and different diets was found. Finally, no differences between experimental diets were evidenced for the haematological parameters.

Keywords

• Pig, Aflatoxin b1, Ochratoxin a, Glucomannan polymer.