Nature Communications (Feb 2019)

N-formyl-stabilizing quasi-catalytic species afford rapid and selective solvent-free amination of biomass-derived feedstocks

  • Hu Li,
  • Haixin Guo,
  • Yaqiong Su,
  • Yuya Hiraga,
  • Zhen Fang,
  • Emiel J. M. Hensen,
  • Masaru Watanabe,
  • Richard Lee Smith

DOI
https://doi.org/10.1038/s41467-019-08577-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Processes for efficient production of primary, secondary or ternary aminated compounds are constant challenges for chemical and pharmaceutical industries. Here, the authors develop selective and sustainable amination chemistry widely applicable to chemical substrates via formic acid.