ACS Central Science (Jul 2023)
Naturally Occurring Mutations of SARS-CoV‑2 Main Protease Confer Drug Resistance to Nirmatrelvir
- Yanmei Hu,
- Eric M. Lewandowski,
- Haozhou Tan,
- Xiaoming Zhang,
- Ryan T. Morgan,
- Xiujun Zhang,
- Lian M. C. Jacobs,
- Shane G. Butler,
- Maura V. Gongora,
- John Choy,
- Xufang Deng,
- Yu Chen,
- Jun Wang
Affiliations
- Yanmei Hu
- Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, New Brunswick, New Jersey, United States
- Eric M. Lewandowski
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Haozhou Tan
- Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, New Brunswick, New Jersey, United States
- Xiaoming Zhang
- Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma, United States
- Ryan T. Morgan
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Xiujun Zhang
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Lian M. C. Jacobs
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Shane G. Butler
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Maura V. Gongora
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- John Choy
- Department Biology, School of Arts and Sciences, the Catholic University of America, Washington,, DC, United States
- Xufang Deng
- Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma, United States
- Yu Chen
- Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States
- Jun Wang
- Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, New Brunswick, New Jersey, United States
- DOI
- https://doi.org/10.1021/acscentsci.3c00538
- Journal volume & issue
-
Vol. 9,
no. 8
pp. 1658 – 1669
Abstract
No abstracts available.
