The involvement of T lymphocytes in the pathogenesis of endometriotic tissues overgrowth in women with endometriosis

Abstract

Background: Endometriosis, uncontrolled proliferation of ectopic and eutopic endometriotic tissues, is common in women at reproductive age, and may affect fertility. The role of macrophages in the pathogenesis is well proved, but engagement of T cells in the pathogenesis of endometriosis is a matter of controversy

Keywords

• Endometriosis
• T-regulatory cells
• Diminished IFN-γ production
• NK cells
• Increased IL-4 production.