Granular Cell Tumour Masquerading as Carcinoma Breast

Abstract

Granular Cell Tumour (GCT) is a rare benign tumour that affects head and neck, the most frequent site being the tongue. GCT with localisation to breast is very rare with an incidence of 4-6%. It is an uncommon cause of breast mass in premenopausal women. The usual clinical presentation is with a painless solitary nodule. But rarely the lesions can be multifocal as a manifestation of a multicentric disease. On clinical and radiological examination, GCT can be confused with infiltrating carcinoma, therefore making its diagnosis challenging for the clinicians, radiologists and pathologists. It is pertinent to differentiate this tumour from other malignant tumours of the breast and avoid misdiagnosing as mammary carcinoma. Definitive preoperative diagnosis helps to prevent unnecessary mastectomy. We report a breast lump in a post-menopausal woman, which was mimicking malignancy clinically and radiologically, but on histopathological examination was diagnosed as a GCT.

Keywords

• periodic acid schiff diastase
• schwann cell derived neoplasm
• s100 protein
• wide local excision