Nature Communications (Feb 2017)

Quantifying cerebral contributions to pain beyond nociception

  • Choong-Wan Woo,
  • Liane Schmidt,
  • Anjali Krishnan,
  • Marieke Jepma,
  • Mathieu Roy,
  • Martin A. Lindquist,
  • Lauren Y. Atlas,
  • Tor D. Wager

DOI
https://doi.org/10.1038/ncomms14211
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 14

Abstract

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Pain is affected by cerebral processes in addition to afferent nociceptive input. Here the authors develop an fMRI-based signature that predicts pain independent of the intensity of nociceptive signals and mediates the pain-modulating effects of several cognitive interventions.