Role of Nutraceuticals in COVID-19 Mediated Liver Dysfunction
Mohammed Sikander,
Shabnam Malik,
Anyssa Rodriguez,
Murali M. Yallapu,
Acharan S. Narula,
Sanjaya K. Satapathy,
Vijian Dhevan,
Subhash C. Chauhan,
Meena Jaggi
Affiliations
Mohammed Sikander
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
Shabnam Malik
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
Anyssa Rodriguez
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
Murali M. Yallapu
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
Acharan S. Narula
Narula Research, LLC, 107 Boulder Bluff, Chapel Hill, NC 27516, USA
Sanjaya K. Satapathy
Division of Hepatology, Department of Internal Medicine, Sandra Atlas Bass Center for Liver Diseases and Transplantation, Barbara and Zucker School of Medicine, Northwell Health, Manhasset, NY 11030, USA
Vijian Dhevan
Department of Surgery, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA
Subhash C. Chauhan
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
Meena Jaggi
Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA
COVID-19 is known as one of the deadliest pandemics of the century. The rapid spread of this deadly virus at incredible speed has stunned the planet and poses a challenge to global scientific and medical communities. Patients with COVID-19 are at an increased risk of co-morbidities associated with liver dysfunction and injury. Moreover, hepatotoxicity induced by antiviral therapy is gaining importance and is an area of great concern. Currently, alternatives therapies are being sought to mitigate hepatic damage, and there has been growing interest in the research on bioactive phytochemical agents (nutraceuticals) due to their versatility in health benefits reported in various epidemiological studies. Therefore, this review provides information and summarizes the juncture of antiviral, immunomodulatory, and hepatoprotective nutraceuticals that can be useful during the management of COVID-19.
