Radiology Case Reports (Jul 2024)

Atypical brain MRI findings in a patient with treatment responsive anti-IgLON5 disease

  • Moein Zandiehvakili,
  • Cathy Kexin Cui,
  • Bronte Jeffrey,
  • Florence Ching-Fen Chang,
  • Jonathan Emerson,
  • Samuel Conyngham

Journal volume & issue
Vol. 19, no. 7
pp. 2613 – 2616

Abstract

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Anti-IgLON5 disease is a rare autoimmune neurological condition which was relatively recently described in the literature. This syndrome encompasses a range of clinical manifestations with most cases showing unremarkable findings on brain magnetic resonance imaging (MRI). Here, we report a case of a 61-year-old female patient with unique brain MRI features that, to the best of our knowledge, has not been reported in the literature before. Following treatment including immunotherapy, the patient experienced significant improvement clinically accompanied by radiological improvement on the follow-up imaging.

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