P409: BCL-2/BCL-XL INHIBITION INDUCES APOPTOSIS AND CIRCUMVENTS VENETOCLAX RESISTANCE IN TP53-MUTATED ACUTE MYELOID LEUKEMIA

• Ida Vänttinen,
• Sari Kytölä,
• Olli Dufva,
• Monica Hellesøy,
• Stein-Erik Gullaksen,
• Tanja Ruokoranta,
• Oscar Brück,
• Sanna Siitonen,
• Pia Ettala,
• Marja Pyörälä,
• Johanna Rimpilainen,
• Timo Siitonen,
• Bjorn Tore Gjertsen,
• Caroline Heckman,
• Heikki Kuusanmäki,
• Mika Kontro

Affiliations

Ida Vänttinen

1 University of Helsinki, Institute for Molecular Medicine Finland, Helsinki, Finland

Sari Kytölä

3 Helsinki University Hospital Comprehensive Cancer Center, Department of Hematology, Helsinki, Finland

Olli Dufva

4 University of Helsinki, Hematology Research Unit, Helsinki, Finland

Monica Hellesøy

5 Helse Bergen, Department of Medicine, Bergen, Norway

Stein-Erik Gullaksen

5 Helse Bergen, Department of Medicine, Bergen, Norway

Tanja Ruokoranta

1 University of Helsinki, Institute for Molecular Medicine Finland, Helsinki, Finland

Oscar Brück

4 University of Helsinki, Hematology Research Unit, Helsinki, Finland

Sanna Siitonen

6 University of Helsinki and Helsinki University Hospital, Department of Clinical Chemistry, Helsinki, Finland

Pia Ettala

7 Turku University Hospital, Department of Clinical Hematology, Turku, Finland

Marja Pyörälä

8 Kuopio University Hospital, Department of Medicine, Kuopio, Finland

Johanna Rimpilainen

9 Tampere University Hospital, Department of Internal Medicine, Tampere, Finland

Timo Siitonen

10 Oulu University Hospital, Cancer Center, Hematology, Oulu, Finland

Bjorn Tore Gjertsen

5 Helse Bergen, Department of Medicine, Bergen, Norway

Caroline Heckman

1 University of Helsinki, Institute for Molecular Medicine Finland, Helsinki, Finland

Heikki Kuusanmäki

1 University of Helsinki, Institute for Molecular Medicine Finland, Helsinki, Finland

Mika Kontro

1 University of Helsinki, Institute for Molecular Medicine Finland, Helsinki, Finland