S135: CRISPR/CAS9 EDITING REVEALS DEPENDENCE OF HUMAN RICHTER SYNDROME AND MURINE CLL CELLS ON SIGNALS FROM B CELL RECEPTOR, CXCR4 RECEPTOR AND MACROPHAGES BUT NOT FROM TOLL-LIKE RECEPTORS IN VIVO
C. Martines,
S. Chakraborty,
V. Guastafierro,
M. Vujovikj,
T. Vaisitti,
S. Deaglio,
L. Laurenti,
A. Dimovski,
D. Efremov
Affiliations
C. Martines
1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
S. Chakraborty
1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
V. Guastafierro
1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
M. Vujovikj
2 Research Center for Genetic Engineering and Biotechnology, Macedonian Academy of Sciences and Arts, Skopje, North Macedonia, Republic of
T. Vaisitti
3 Functional Genomics Unit, Department of Medical Sciences, University of Turin, Torino
S. Deaglio
3 Functional Genomics Unit, Department of Medical Sciences, University of Turin, Torino
L. Laurenti
4 Department of Hematology, Catholic University Hospital “A. Gemelli”, Rome, Italy
A. Dimovski
2 Research Center for Genetic Engineering and Biotechnology, Macedonian Academy of Sciences and Arts, Skopje, North Macedonia, Republic of
D. Efremov
1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy