Case report: An autopsy case of pilsicainide poisoning

Sella Takei; Hiroshi Kinoshita; Mitsuru Kumihashi; Mostofa Jamal; Hiroko Abe; Shoji Kimura

doi:10.3389/fphar.2023.1090265

Frontiers in Pharmacology (Jan 2023)

Case report: An autopsy case of pilsicainide poisoning

Sella Takei,
Hiroshi Kinoshita,
Mitsuru Kumihashi,
Mostofa Jamal,
Hiroko Abe,
Shoji Kimura

Affiliations

Sella Takei: Department of Forensic Medicine Faculty of Medicine, Kagawa University, Kagawa, Japan
Hiroshi Kinoshita: Department of Forensic Medicine Faculty of Medicine, Kagawa University, Kagawa, Japan
Mitsuru Kumihashi: Department of Forensic Medicine Faculty of Medicine, Kagawa University, Kagawa, Japan
Mostofa Jamal: Department of Forensic Medicine Faculty of Medicine, Kagawa University, Kagawa, Japan
Hiroko Abe: Bio Design Inc., Tokyo, Japan
Shoji Kimura: Department of Forensic Medicine Faculty of Medicine, Kagawa University, Kagawa, Japan

DOI: https://doi.org/10.3389/fphar.2023.1090265
Journal volume & issue: Vol. 14

Abstract

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We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy findings, results of the toxicological examination, and investigation by the authorities, we concluded that the cause of death was due to pilsicainide poisoning.

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

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