High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells

• Yuji Takihara,
• Ayako Nakamura-Ishizu,
• Darren Qiancheng Tan,
• Masahiro Fukuda,
• Takayoshi Matsumura,
• Mitsuhiro Endoh,
• Yuichiro Arima,
• Desmond Wai Loon Chin,
• Terumasa Umemoto,
• Michihiro Hashimoto,
• Hidenobu Mizuno,
• Toshio Suda

Affiliations

Yuji Takihara

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Ayako Nakamura-Ishizu

Cancer Science Institute of Singapore, National University of Singapore, Singapore; International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan

Darren Qiancheng Tan

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Masahiro Fukuda

International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan; Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, Singapore

Takayoshi Matsumura

Cancer Science Institute of Singapore, National University of Singapore, Singapore

Mitsuhiro Endoh

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pluripotent Stem Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan

Yuichiro Arima

International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan

Desmond Wai Loon Chin

Genome Institute of Singapore, Singapore

Terumasa Umemoto

International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan

Michihiro Hashimoto

International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan

Hidenobu Mizuno

International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan

Toshio Suda

Cancer Science Institute of Singapore, National University of Singapore, Singapore; International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan; Toshio Suda, Cancer Science Institute of Singapore, Centre for Translational Medicine, National University of Singapore, 14 Medical Dr, #12-01, Singapore 117599, Singapore