Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR‑2 Inhibitors

• Lamya H. Al-Wahaibi,
• Ali M. Elshamsy,
• Taha F. S. Ali,
• Bahaa G. M. Youssif,
• Stefan Bräse,
• Mohamed Abdel-Aziz,
• Nawal A. El-Koussi

Affiliations

Lamya H. Al-Wahaibi

Department of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia

Ali M. Elshamsy

Pharmceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt

Taha F. S. Ali

Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt

Bahaa G. M. Youssif

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Stefan Bräse

Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, Karlsruhe, Germany

Mohamed Abdel-Aziz

Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt

Nawal A. El-Koussi

Pharmceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt