Generation and characterization of a human induced pluripotent stem cell line (SDQLCHi052-A) from peripheral blood mononuclear cells derived from a healthy Chinese donor

Zirui Wan; Jingyun Guan; Yue Li; Haiyan Zhang; Bin Wang; Xiaomeng Yang; Xiaohua Jin; Xu Ma; Yi Liu

Stem Cell Research (Sep 2023)

Generation and characterization of a human induced pluripotent stem cell line (SDQLCHi052-A) from peripheral blood mononuclear cells derived from a healthy Chinese donor

Zirui Wan,
Jingyun Guan,
Yue Li,
Haiyan Zhang,
Bin Wang,
Xiaomeng Yang,
Xiaohua Jin,
Xu Ma,
Yi Liu

Affiliations

Zirui Wan: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China; National Research Institute for Family Planning, Beijing 100081, China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China; National Human Genetic Resources Center, Beijing 102206, China
Jingyun Guan: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Yue Li: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Haiyan Zhang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Bin Wang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Xiaomeng Yang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China
Xiaohua Jin: National Research Institute for Family Planning, Beijing 100081, China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China; National Human Genetic Resources Center, Beijing 102206, China; Corresponding authors at: National Research Institute for Family Planning, Beijing 100081, China (X. Jin and X. Ma); Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China (Y. Liu).
Xu Ma: National Research Institute for Family Planning, Beijing 100081, China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China; National Human Genetic Resources Center, Beijing 102206, China; Corresponding authors at: National Research Institute for Family Planning, Beijing 100081, China (X. Jin and X. Ma); Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China (Y. Liu).
Yi Liu: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China; Corresponding authors at: National Research Institute for Family Planning, Beijing 100081, China (X. Jin and X. Ma); Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Ji’nan 250022, China (Y. Liu).

Journal volume & issue: Vol. 71
p. 103139

Abstract

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A non-integrated induced pluripotent stem cell (iPSC) line was generated derived from a healthy 20-day-old male using peripheral blood mononuclear cells. The established induced pluripotent stem cell line possesses a normal karyotype, expresses pluripotency markers and able to differentiate into all three germ layers in vitro. This cell line could serve as a health control or a basis for disease modeling, to explore molecular pathogenesis.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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