Current aspects of radiobiology in modern radiotherapy - our clinical experience

Abstract

Personalized radiation treatment is an important goal in radiation oncology. As a result, one of the main challenges in radiobiology today is predicting a patient’s tissue radiosensitivity so that a personalized treatment can be tailored to that individual. For the first time since 2016, a group from the Institute of Oncology and Radiology of Serbia has begun performing translational research in the field of radiobiology. The aim of these studies is to identify molecular markers important for the prediction of radiosensitivity as well as the occurrence of toxic effects of radiotherapy. In the past five years, significant international cooperation has been established with the Radiogenomic Consortium, as well as leading European and world experts in this field. In addition, during this period, several significant and promising results in this field were published, and a Laboratory for Radiobiology was established at the Institute of Oncology and Radiology of Serbia.

Keywords

• radiosensitivity
• radiotoxicity
• radiogenomics consortium