Nature Communications (Nov 2022)

The molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane

  • Claudia Matthaeus,
  • Kem A. Sochacki,
  • Andrea M. Dickey,
  • Dmytro Puchkov,
  • Volker Haucke,
  • Martin Lehmann,
  • Justin W. Taraska

DOI
https://doi.org/10.1038/s41467-022-34958-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 19

Abstract

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Caveolae can bend and flatten, but how this is regulated is not well understood. Authors use correlative super-resolution light and electron microscopy to map the key proteins that mediate curvature of the caveolar coat.