Depression in Parkinson's disease as the key factor of deterioration in quality of life: pathophysiology, diagnostics and treatment

Abstract

Parkinson's disease (PD) is multisystem neurodegenerative disorder with a wide range of motor, nervous and mental disorders. On average, depression occurs in 40-50% of patients with Parkinson's disease and is a major factors of deterioration of life quality. The article tells about present-day knowledge about the disease pattern, pathophysiology and approaches to the treatment of depression in Parkinson's disease.

Keywords

• болезнь паркинсона
• депрессия
• клиника
• патофизиология
• диагностика
• терапия
• parkinson's disease
• depression
• disease pattern
• pathophysiology
• diagnostics
• therapy