Adult onset Leigh syndrome

Abstract

Leigh syndrome is a rare progressive mitochondrial disorder of oxidative metabolism. Though it has been reported in infancy and childhood, it is rarely described in adults. The authors describe a patient who had clinical and magnetic resonance imaging features diagnostic of Leigh syndrome, with supportive biochemical and muscle histochemistry evidence.

Keywords

• Deafness
• Leigh syndrome
• magnetic resonance imaging
• mitochondrial cytopathy
• ptosis