Added value of histogram analysis of ADC in predicting radiation-induced temporal lobe injury of patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy

Abstract

Key points Histogram parameters from pretreatment ADC maps are associated with RTLI in NPC. The ADC and combined models show better performance than the T stage alone. The combined model shows excellent performance in predicting RTLI in different subgroups.

Keywords

• Nasopharyngeal carcinoma
• Diffusion-weighted MRI
• Temporal lobe
• Radiation therapy
• Radiomics