Semina: Ciências Exatas e Tecnológicas (Oct 2014)

Electrochemical study of oxidation process of promethazine using sensor based on carbon nanotubes paste containing immobilized DNA on inorganic matrix

  • João Paulo Marco,
  • Keyller Bastos Borges,
  • César Ricardo Teixeira Tarley,
  • Emerson Schwingel Ribeiro,
  • Arnaldo César Pereira

DOI
https://doi.org/10.5433/1679-0375.2014v35n2p215
Journal volume & issue
Vol. 35, no. 2
pp. 215 – 230

Abstract

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In the present work the voltammetric behavior and the oxidation process of promethazine (PHZ) in electrochemical sensor based on carbon nanotubes paste containing DNA immobilized on the inorganic matrix prepared by sol-gel process (SiO2/Al2O3/Nb2O5). The method of Laviron verified that the system is irreversible and high speed of electron transfer between the electrode and DNA. The study of the oxidation of PHZ and influence of pH showed slope of 0.054 V / pH (near the nernstian system: 0.0592 V / pH) suggesting that it involves the transfer of two protons and two electrons.

Keywords