Journal of the Formosan Medical Association (Aug 2017)

Anemia and hematinic deficiencies in gastric parietal cell antibody-positive and -negative oral mucosal disease patients with microcytosis

  • Hung-Pin Lin,
  • Yu-Hsueh Wu,
  • Yi-Ping Wang,
  • Yang-Che Wu,
  • Julia Yu-Fong Chang,
  • Andy Sun

DOI
https://doi.org/10.1016/j.jfma.2017.02.001
Journal volume & issue
Vol. 116, no. 8
pp. 613 – 619

Abstract

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Microcytosis is defined as mean corpuscular volume (MCV) 5 × 1012/L than healthy controls. Moreover, 19 of 30 GPCA+/microcytosis patients and 143 of 210 GPCA−/microcytosis patients had anemia, with iron deficiency anemia being the most common type, followed by thalassemia trait-induced anemia and microcytic anemia due to other causes. Conclusion: We conclude that GPCA in microcytosis patients' sera may have caused significantly lower mean vitamin B12 level as well as significantly higher mean RDW and serum homocysteine level in our GPCA+/microcytosis patients than in GPCA−/microcytosis patients. Herein, iron deficiency anemia was the most common type of anemia in anemic GPCA+/microcytosis and GPCA−/microcytosis patients.

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