Possible Oncogenic Viruses Associated with Lung Cancer

Abstract

Yan Hu,1 Siying Ren,2 Yu He,1 Li Wang,1 Chen Chen,1 Jingqun Tang,1 Wenliang Liu,1 Fenglei Yu1 1Department of Thoracic Surgery, The Thoracic Surgery Research Room, Second Xiangya Hospital, Central South University, Changsha 410011, People’s Republic of China; 2Department of Respiratory Medicine, Hunan Centre for Evidence-Based Medicine, Research Unit of Respiratory Diseases, Second Xiangya Hospital, Central South University, Changsha 410011, People’s Republic of ChinaCorrespondence: Fenglei YuDepartment of Thoracic Surgery, The Thoracic Surgery Research Room, Second Xiangya Hospital, Central South University, No. 139 Renmin Road, Changsha 410011, People’s Republic of ChinaEmail [email protected]: Lung cancer is the most common cause of cancer death worldwide. Tobacco smoking is the most predominant etiology for lung cancer. However, only a small percentage of heavy smokers develop lung cancer, which suggests that other cofactors are required for lung carcinogenesis. Viruses have been central to modern cancer research and provide profound insights into cancer causes. Nevertheless, the role of virus in lung cancer is still unclear. In this article, we reviewed the possible oncogenic viruses associated with lung cancer.Keywords: oncogenic virus, lung cancer, human papillomavirus, Merkel cell polyomavirus, Epstein–Barr virus, jaagsiekte sheep virus, John Cunningham virus

Keywords

• oncogenic virus
• lung cancer
• human papillomavirus
• merkel cell polyomavirus
• epstein-barr virus
• jaagsiekte sheep virus
• john cunningham virus