Фармакокинетика и Фармакодинамика (Feb 2019)

Influence of probiotic lactobacilli on nonspecific resistance and physiological parameters of laboratory animals

  • A. N. Ovcharova,
  • O. V. Safronova,
  • L. L. Polyakova

DOI
https://doi.org/10.24411/2587-7836-2019-10043
Journal volume & issue
Vol. 0, no. 2
pp. 28 – 31

Abstract

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Ovcharova AN, Safronova OV, Polyakova LL All-Russian Research Institute of Physiology, Biochemistry and Nutrition of animals - branch of Federal state budgetary scientific institution "Federal Research Center Livestock - AUIAB Academician LK Ernst", Borovsk, Kaluga region, Russian Federation Resume. For the correction and prevention of microflora disorders are widely used microbial preparations - probiotics, which have a positive effect on the composition of the intestinal microflora, the immune system of animals. Lactobacilli play a special role in the formation of normal microflora. In 2009. in the laboratory of biotechnology of microorganisms vniifbip was made Association of four strains of lactobacilli: Lactobacillus casei LBR 1/90 (VCM-2780D), Lactobacillus paracasei LBR 5/90 (VCM-2781D), Lactobacillus rhamnosus LBR 33/90 (VCM-11277), Lactobacillus rhamnosus LBR 44/90 (VCM-11278), isolated from the digestive tract of Calves, called tetralactobacterin (TLB). The strains included in probiotics are non-pathogenic and have a wide range of antagonistic activity against bacteria of the genera Staphylococcus, Streptococcus, Escherichia and Salmonella. The aim of this work was to study the effect of tetrasaccharide on nonspecific immunity and physiological parameters of rabbits.

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