Nature Communications (Nov 2018)

Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

  • Brigitta M. Laksono,
  • Rory D. de Vries,
  • R. Joyce Verburgh,
  • Eline G. Visser,
  • Alwin de Jong,
  • Pieter L. A. Fraaij,
  • Wilhemina L. M. Ruijs,
  • David F. Nieuwenhuijse,
  • Henk-Jan van den Ham,
  • Marion P. G. Koopmans,
  • Menno C. van Zelm,
  • Albert D. M. E. Osterhaus,
  • Rik L. de Swart

DOI
https://doi.org/10.1038/s41467-018-07515-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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The mechanisms by which measles virus infection induces transient immune suppression in humans are poorly understood. Here, Laksono and colleagues characterise the pathogenesis of measles-associated immune suppression in unvaccinated children, and shed new light on the long-term effects of measles on the host.