Parasites & Vectors (Mar 2024)

Control of Rhipicephalus microplus on taurine cattle with fluralaner in a subtropical region

  • Tiago Gallina,
  • Camila dos Santos Lagranha,
  • Giancarlo Bilo,
  • Cristiano Malavolta,
  • Lorena Lopes Ferreira,
  • Fernando de Almeida Borges,
  • Daniel de Castro Rodrigues,
  • Tom Strydom,
  • Siddartha Torres,
  • Emmanuel Arnhold,
  • Welber Daniel Zanetti Lopes

DOI
https://doi.org/10.1186/s13071-024-06200-0
Journal volume & issue
Vol. 17, no. 1
pp. 1 – 8

Abstract

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Abstract Background In Rio Grande do Sul, Brazil, a region with a subtropical climate, Rhipicephalus microplus is present in taurine cattle raised for beef and milk. In addition, ticks resistant to multiple acaricides are present in this region. Recently, fluralaner (isoxazoline) was launched on the market. Thus, there is a need to evaluate the effects of fluralaner for the control of R. microplus on taurine cattle. In addition, occurrence of myiasis by Cochliomyia hominivorax larvae after tick parasitism and weight gain of cattle during the experimental period were evaluated. Methods Thirty naturally infested cattle were divided into two experimental groups: T01, treated with fluralaner (2.5 mg/kg) pour-on; T02, control. T01 received fluralaner on Days 0 (early summer in January), 42 and 84 (early autumn), whereas T02, a control group, received palliative treatment with a spray formulation when the group mean was ≥ 30 ticks. Counts of R. microplus females and calculation of the efficacy of fluralaner were performed on Days 3, 7, 14, 28, 35, 42, 56, 70, 84, 98, 112 and 126. The occurrence of myiasis was assessed throughout the study period. In addition, the weight, weight gain and daily weight gain of the animals were evaluated. Results In the 12 evaluations performed, the parasitic load of T01 was near zero. Fluralaner showed 99.5% efficacy on the 3rd day after the first treatment and 100% efficacy from Day 7 to Day 126. Cochliomyia hominivorax larvae (n = 6; p = 0.0251) were found only in the control group (T02). At the end of the study, the animals subjected to treatments with fluralaner gained 32.8 kg more than the animals in the control group. Conclusions Application of fluralaner in summer and autumn, with 42-day intervals between treatments, was effective to control R. microplus on taurine cattle, which also gained more weight than control cattle. Additionally, no cases of myasis were documented in animals treated with fluralaner. Graphical Abstract

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