Hemorrhage from Meckel’s diverticulum is very rare in adults. However, it should not be overlooked as a possible cause of gastrointestinal bleeding, since hemorrhage from Meckel’s diverticulum can be acute and massive. We report a case a 29-year-old man having Meckel’s diverticulum in with life-threatening hemorrhage. This case emphasizes the potential role of transcatheter arterial embolization during the early detection period, and proper management of massive hemorrhage from Meckel's diverticulum