RUDN Journal of Medicine (Dec 2012)
Comparative study of testicular tissue reparative peculiarities on the model of bilateral abdominal cryptorchism in young and mature animals
Abstract
Pathomorphological changes in the testes of the animal of different age groups with experimentally modeled cryptorchism are investigated. All animals were divided into 3 groups according to the time of fixation of testes in the abdominal cavity (for 2, 3 and 4 weeks). Alterations were fixed at the moment of the bringing down of testes into the scrotum, on the 14 th and the 28 th days with the consequent estimation of pathomorphological changes and dynamics of reparative potential of testicular tissue. Revealed that experimental cryptorchism leads to the significant degenerate changes in the testes, up to destruction of testicular tissue elements in animals both groups. Comparative analysis of reparative possibilities showed that in the young animals the recovery potential of testicular tissue is much higher than in mature animals.