Journal of Pain Research (Mar 2024)
Effect of Intermittent Thoracic Paravertebral Block on Postoperative Nausea and Vomiting Following Thoracoscopic Radical Resection of the Lung Cancer: A Prospective Randomized Trial
Abstract
Ting Ma,1,* Yulong Yu,2,* Haihua Cao,3 Huiqin Wang,2 Mingcang Wang2 1Anesthesia Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310000, People’s Republic of China; 2Anesthesia Department, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, 317000, People’s Republic of China; 3Obstetrical Department, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, 317000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingcang Wang, Anesthesia Department, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, No. 150, Ximen Street, Linhai, Zhejiang, 317000, People’s Republic of China, Email [email protected]: To explore the benefits of ultrasound-guided intermittent thoracic paravertebral block (TPVB) combined with intravenous analgesia (PCIA) in alleviating postoperative nausea and vomiting (PONV) during video-assisted thoracic surgery (VATS).Patients and Methods: 120 patients with lung carcinoma undergoing VATS were included and divided into three groups: group S (single TPVB+PCIA), group I (intermittent TPVB+PCIA), and group P (PCIA). The patients’ NRS scores, postoperative hydromorphone hydrochloride consumption, and intramuscular injection of bucinnazine hydrochloride were recorded. The incidence of PONV and complications were documented.Results: Compared with the group P, both group I and group S had significantly lower static NRS scores from 1– 48 hours after the operation (P < 0.05), and the dynamic NRS score of group I at the 1– 48 hours after the operation were significantly decreased (P < 0.05). Compared with the group P, the proportion of patients with PONV in group I was significantly lower (P < 0.05), while there was no significant difference in group S. Moreover, the hospitalization period of patients in group I was significantly reduced compared with the other two groups (P < 0.01), and the patient satisfaction was significantly increased compared with the group P (P < 0.05).Conclusion: Intermittent TPVB combined with PCIA can reduce the postoperative pain and the occurrence of PONV.Keywords: thoracic paravertebral block, patient-controlled intravenous analgesia, video-assisted thoracic surgery, postoperative nausea and vomiting, postoperative pain
