Cardiovascular disease in climacteric women with psycho-emotional disorders

Abstract

Aim. To assess psycho-emotional disorder (PED) impact on cardiovascular system status in climacteric women. Material and methods. This case-control study included 186 climacteric women with manifested PED. All participants gave their informed consent. The control group included 186 women without PED. Menopause syndrome severity was assessed with modified menopausal index. Depression was diagnosed according to ICD-10; its severity was assessed with Beck’s Depression Inventory and Hospital Anxiety and Depression Scale. Results. In all 186 women from the main group, depression was diagnosed, climacteric syndrome (CS) was more severe, and apolipoprotein B level was higher than in controls. Cardiovascular disease (CVD) and vascular event risk was significantly higher in depressed patients. Conclusion. In climacteric women, depression increased CVD risk and aggravated CS clinical course.

Keywords

• сlimacteric period
• case-control study
• depression
• cardiovascular disease